Genome Property Definition Page

NameCRISPR system, I-B subtype, Hmari branch
DescriptionCRISPR repeats are by definition Clustered Regularly Interspaced Short Palindromic Repeats, described by Jansen [1]. Certain proteins, including Cas1 to Cas4, are found only in genomes with CRISPR repeats, and are near these repeats. Jansen, et al. describe CRISPR loci as having direct repeats, varying in size from 21 to 37 bp, interspaced by similarly sized non-repetitive sequences. Variants of CRISP/Cas loci (subtypes) have been described (Haft, Selengut, et al., submitted) in which certain groups of subtype-specific genes are found in addition to characteristic sets of the more widely distributed cas genes. The Hmari subtype, so named because this subtype is the only one found in the genome of Haloarcula marismortui ATCC 43049, consists of cas1-6 and the subtype specific genes csh1-2. The repeats associated with this subtype tend to have a periodicity of 66 nucleotides. This subtype is found both in Archaea and Bacteria.
JCVI RoleOther
Parent PropertyGenProp0021: CRISPR region
Literature References
[ 1 ]Haft DH, Selengut J, Mo ngodin EF, Nelson KE  A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes.  PLoS Comput Biol. 2005 Nov;1(6):e60.  PMID 16292354

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
Cas1, Hmari regionCas1YESTIGR00287 (HMM-CLUST): CRISPR-associated endonuclease Cas1
Cas2, Hmari regionCas2YESTIGR01573 (HMM-CLUST): CRISPR-associated endonuclease Cas2
Cas3, Hmari regionCas3YESTIGR01587 (HMM-CLUST): CRISPR-associated helicase Cas3
Cas4, Hmari regionCas4YESTIGR00372 (HMM-CLUST): CRISPR-associated protein Cas4
Cas5, Hmari subtype specific variantCas5hYESTIGR02592 (HMM): CRISPR-associated protein Cas5, subtype I-B/HMARI
Cas6, Hmari regionCas6YESTIGR01877 (HMM-CLUST): CRISPR-associated endoribonuclease Cas6
Csh1 family, TIGR02591Csh1YESTIGR02591 (HMM): CRISPR-associated protein Cas8b/Csh1, subtype I-B/HMARI
Csh2 family, TIGR02590Csh2YESTIGR02590 (HMM): CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI

Parent Properties
GenProp0021CRISPR region

Sibling Properties
GenProp0310CRISPR system, I-F/Ypest subtype
GenProp0313CRISPR system, I-C/Dvulg subtype
GenProp0314CRISPR system, II/Nmeni subtype
GenProp0315CRISPR system, I-E/Ecoli subtype
GenProp0316CRISPR system, III-B/RAMP module subtype
GenProp0317CRISPR system, I-B subtype, Tneap branch
GenProp0318CRISPR system, III-A/Mtube subtype
GenProp0319CRISPR system, I-A/Apern subtype
GenProp0469CRISPR system, Dpsyc subtype
GenProp0670CRISPR system, Aferr subtype
GenProp0685CRISPR system, I-D/Cyano subtype
GenProp0768CRISPR system, Pging subtype
GenProp0922CRISPR system, Myxan subtype
GenProp1061CRISPR system, PreFran subtype