Genome Property Definition Page

NameCRISPR system, III-B/RAMP module subtype
DescriptionCRISPR repeats are by definition Clustered Regularly Interspaced Short Palindromic Repeats, described by Jansen [1]. Certain proteins, including Cas1 to Cas4, are found only in genomes with CRISPR repeats, and are near these repeats. The repeats vary in size from 24 to 48 bp, interspaced by similarly sized non-repetitive sequences. Variants of CRISP/Cas loci (subtypes) have been described (Haft, et al., 2005 in which certain groups of subtype-specific genes are found in addition to characteristic sets of the more widely distributed cas genes. These subtype-specific genes are found proximal to the cas core genes and the CRISPR repeats. Unlike these, the set of CRISPR-associated genes represented here are always found in in genomes which also contain CRISPRs, but may be located at a remote site on the genome from the core genes and repeats. Several of these genes belong to the RAMP (Repeat-Associated Mystery Protein) family, so this 6-gene cassette is called the CRISPR RAMP module.
JCVI RoleOther
Parent PropertyGenProp0021: CRISPR region
Literature References
[ 1 ]Saunders NF, Goodchild A, Raftery M, Guilhaus M, Curmi PM, Cavicchioli R  Predicted roles for hypothetical proteins in the low-temperature expressed proteome of the Antarctic archaeon Methanococcoides burtonii.  J Proteome Res 2005 Mar-Apr;4(2):464-72.  PMID 15822923
[ 2 ] Haft DH, Selengut J, Mongodin EF, Nelson KE   A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes. FAU - Haft, Daniel H AU - Haft DH FAU - Selengut, Jeremy AU - Selengut J FAU - Mongodin, Emmanuel F AU - Mongodin EF FAU - Nelson, Karen   PLoS Comput Biol. 2005 Nov;1(6):e60.  PMID 16292354

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
Cmr1Cmr1YESTIGR01894 (HMM): CRISPR type III-B/RAMP module RAMP protein Cmr1
Cmr2Cmr2YESTIGR02577 (HMM): CRISPR-associated protein Cas10/Cmr2, subtype III-B
Cmr3Cmr3YESTIGR01888 (HMM): CRISPR type III-B/RAMP module-associated protein Cmr3
Cmr4Cmr4YESTIGR02580 (HMM): CRISPR type III-B/RAMP module RAMP protein Cmr4
Cmr5Cmr5YESTIGR01881 (HMM): CRISPR type III-B/RAMP module-associated protein Cmr5
Cmr6Cmr6YESTIGR01898 (HMM): CRISPR type III-B/RAMP module RAMP protein Cmr6

Parent Properties
GenProp0021CRISPR region

Sibling Properties
GenProp0310CRISPR system, I-F/Ypest subtype
GenProp0313CRISPR system, I-C/Dvulg subtype
GenProp0314CRISPR system, II/Nmeni subtype
GenProp0315CRISPR system, I-E/Ecoli subtype
GenProp0317CRISPR system, I-B subtype, Tneap branch
GenProp0318CRISPR system, III-A/Mtube subtype
GenProp0319CRISPR system, I-A/Apern subtype
GenProp0320CRISPR system, I-B subtype, Hmari branch
GenProp0469CRISPR system, Dpsyc subtype
GenProp0670CRISPR system, Aferr subtype
GenProp0685CRISPR system, I-D/Cyano subtype
GenProp0768CRISPR system, Pging subtype
GenProp0922CRISPR system, Myxan subtype
GenProp1061CRISPR system, PreFran subtype