| Accession | GenProp0316 |
| Name | CRISPR system, III-B/RAMP module subtype |
| Type | SYSTEM |
| Description | CRISPR repeats are by definition Clustered Regularly Interspaced Short Palindromic Repeats, described by Jansen [1]. Certain proteins, including Cas1 to Cas4, are found only in genomes with CRISPR repeats, and are near these repeats. The repeats vary in size from 24 to 48 bp, interspaced by similarly sized non-repetitive sequences. Variants of CRISP/Cas loci (subtypes) have been described (Haft, et al., 2005 in which certain groups of subtype-specific genes are found in addition to characteristic sets of the more widely distributed cas genes. These subtype-specific genes are found proximal to the cas core genes and the CRISPR repeats. Unlike these, the set of CRISPR-associated genes represented here are always found in in genomes which also contain CRISPRs, but may be located at a remote site on the genome from the core genes and repeats. Several of these genes belong to the RAMP (Repeat-Associated Mystery Protein) family, so this 6-gene cassette is called the CRISPR RAMP module. |
| JCVI Role | Other |
| Parent Property | GenProp0021: CRISPR region
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| Literature References | [ 1 ]Saunders NF, Goodchild A, Raftery M, Guilhaus M, Curmi PM, Cavicchioli R Predicted roles for hypothetical proteins in the low-temperature expressed proteome of the Antarctic archaeon Methanococcoides burtonii. J Proteome Res 2005 Mar-Apr;4(2):464-72. PMID 15822923
[ 2 ] Haft DH, Selengut J, Mongodin EF, Nelson KE A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes. FAU - Haft, Daniel H AU - Haft DH FAU - Selengut, Jeremy AU - Selengut J FAU - Mongodin, Emmanuel F AU - Mongodin EF FAU - Nelson, Karen PLoS Comput Biol. 2005 Nov;1(6):e60. PMID 16292354
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| Accession | Name |
|---|
| GenProp0310 | CRISPR system, I-F/Ypest subtype |
| GenProp0313 | CRISPR system, I-C/Dvulg subtype |
| GenProp0314 | CRISPR system, II/Nmeni subtype |
| GenProp0315 | CRISPR system, I-E/Ecoli subtype |
| GenProp0317 | CRISPR system, I-B subtype, Tneap branch |
| GenProp0318 | CRISPR system, III-A/Mtube subtype |
| GenProp0319 | CRISPR system, I-A/Apern subtype |
| GenProp0320 | CRISPR system, I-B subtype, Hmari branch |
| GenProp0469 | CRISPR system, Dpsyc subtype |
| GenProp0670 | CRISPR system, Aferr subtype |
| GenProp0685 | CRISPR system, I-D/Cyano subtype |
| GenProp0768 | CRISPR system, Pging subtype |
| GenProp0922 | CRISPR system, Myxan subtype |
| GenProp1061 | CRISPR system, PreFran subtype |
