Genome Property Definition Page

Namethiamine/TPP ABC transporter ThiBPQ
DescriptionThis property describes a three-component ABC transporter, ThiBPQ, for thiamine and/or thiamine derivatives. It is demonstrated experimentally in Salmonella typhimurium and E. coli (PMID:9535878) and is inferred from gene location next to genes for thiamine salvage enzymes in Brucella suis, Sinorhizobium meliloti, etc. All known examples are in the Proteobacteria.
JCVI RoleOther
Parent PropertyGenProp0180: small molecule transport
Literature References
[ 1 ]Webb E, Claas K, Downs D  thiBPQ encodes an ABC transporter required for transport of thiamine and thiamine pyrophosphate in Salmonella typhimurium.  J Biol Chem 1998 Apr 10;273(15):8946-50.  PMID 9535878
Web ReferencesThiamine metabolism
Gene Ontology TermGO:0015888: thiamine transport (biological_process)
GO:0030974: thiamine pyrophosphate transport (biological_process)

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
thiamine binding proteinbindingYESTIGR01276 (HMM): thiamin/thiamin pyrophosphate ABC transporter, thiamin/thiamin pyrophospate-binding proteinGO:0030974: thiamine pyrophosphate transport
GO:0015888: thiamine transport
thiamine transporter permeasepermaseYESTIGR01253 (HMM): thiamine/thiamine pyrophosphate ABC transporter, permease proteinGO:0030974: thiamine pyrophosphate transport
GO:0015888: thiamine transport
thiamine transporter ATP-binding proteinthiATPYESTIGR01277 (HMM): thiamine ABC transporter, ATP-binding proteinGO:0030974: thiamine pyrophosphate transport
GO:0015888: thiamine transport

Parent Properties
GenProp0180small molecule transport

Sibling Properties
GenProp0119PTS transport system
GenProp0129Na+-translocating NADH-quinone reductase
GenProp0135NADH dehydrogenase I
GenProp0172Potassium-transporting ATPase KdpFABC
GenProp0176TRAP-T (tripartite ATP-independent periplasmic transporters) family transporters
GenProp0190phosphate ABC transporter (pstSCAB-phoU)
GenProp0191sulfate/thiosulfate ABC transporter
GenProp0192molybdate ABC transporter
GenProp0236phosphonates ABC transport
GenProp0279cobalt import systems
GenProp0494nickel import ABC transporter
GenProp0542Tol-Pal system
GenProp0543TonB-dependent transport
GenProp0651ectoine ABC transporter EhuABCD
GenProp0693fructose utilization as fructose-1,6-bisphosphate
GenProp0694glucose utilization as fructose-1,6-bisphosphate
GenProp07122-aminoethylphosphonate (AEP) ABC transporter, type I, PhnSTUV
GenProp07212-aminoethylphosphonate (AEP) ABC transporter, type II
GenProp0743urea ABC transporter UrtABCDE
GenProp0748choline ABC transporter, ChoXWV family
GenProp0749choline sulfate utilization
GenProp0828heme uptake system, NEAT-domain mediated
GenProp0853lantibiotic system, gallidermin/epidermin family
GenProp0873ion-motive antiporter cycles