Genome Property Definition Page
Accession | GenProp0245 | |
Name | chaperone system: GroEL/GroES | |
Type | SYSTEM | |
Description | GroEL and GroES comprise the bacterial group I chaperonin, a toroidal complex involved in folding or refolding proteins in the cytosol. Archaea and Eukaryotes have instead (with a few rare cases of overlap) a group II chaperonin complex, usually called the thermosome in the Archaea and CCT in the Eukaryota. At least one member of the archaeal genus Methanosarcina, has both. | |
JCVI Role | Protein folding and stabilization | |
Parent Property | GenProp0248: protein folding | |
Literature References |
| |
Web References | The Ecocyc Database: Polypeptide: GroEL, chaperone Hsp60, peptide-dependent ATPase, heat shock protein The Ecocyc Database: Polypeptide: GroES, 10 Kd chaperone binds to Hsp60 in pres. Mg-ATP, suppressing its ATPase activity | |
Gene Ontology Term | GO:0006457: protein folding (biological_process) |
Components
Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
---|---|---|---|---|
chaperonin GroEL | GroEL | YES | TIGR02348 (HMM): chaperonin GroL | GO:0006457: protein folding |
co-chaperonin GroES | GroES | YES | PF00166 (HMM): chaperonin GroS | GO:0006457: protein folding |
Parent Properties
Accession | Name |
---|---|
GenProp0248 | protein folding |
Sibling Properties
Accession | Name |
---|---|
GenProp0244 | chaperone system: DnaK-DnaJ-GrpE |
GenProp0246 | chaperone system: thermosome/prefoldin |
GenProp0725 | outer membrane protein assembly complex |
GenProp0928 | OMP chaperone system: SurA-Skp-DegP |