Genome Property Definition Page
| Accession | GenProp0189 |
| Name | tRNA-Gln direct aminoacylation |
| Type | PATHWAY |
| Description | The tRNA for Gln is produced, in different species, in two different ways. In some bacteria (including E. coli), and in the eukaryotic cytosol, the tRNA for glutamine is charged with glutamine. In the majority of sequenced prokaryotes, however, tRNA(gln) initially is mischarged with glutamate (Glu). Glu is subsequently amidated to Gln while on the tRNA(gln), as by GatABC in Bacillus subtilis, resulting in Gln biosynthesis from Glu as well as tRNA aminoacylation. This property describes the pathway of direct Gln--tRNA ligase activity, performed by a single protein, glutaminyl-tRNA synthetase (TIGR00440). |
| JCVI Role | tRNA aminoacylation |
| Parent Property | GenProp0197: protein biosynthesis GenProp0258: tRNA aminoacylation |
| Gene Ontology Term | GO:0006425: glutaminyl-tRNA aminoacylation (biological_process) |
Components
| Step Name | Step Num | Required | Evidence (Method) | Evidence Go Terms |
|---|---|---|---|---|
| glutaminyl-tRNA synthetase | glnS | YES | TIGR00440 (HMM): glutamine--tRNA ligase | GO:0006425: glutaminyl-tRNA aminoacylation |
Parent Properties
| Accession | Name |
|---|---|
| GenProp0197 | protein biosynthesis |
| GenProp0258 | tRNA aminoacylation |
Sibling Properties
| Accession | Name |
|---|---|
| GenProp0016 | selenocysteine system |
| GenProp0312 | pyrrolysine |
| GenProp0132 | transcription termination - antitermination Nus factors |
| GenProp0148 | release factor 2 programmed frameshift |
| GenProp0174 | ribosome, bacterial, large subunit |
| GenProp0175 | ribosome, bacterial, small subunit |
| GenProp0188 | GatABC aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase complex |
| GenProp0211 | tmRNA trans-translation system |
| GenProp0258 | tRNA aminoacylation |
| GenProp0259 | tRNA-Asn direct aminoacylation |
| GenProp0304 | cysteine biosynthesis, tRNA-dependent |
| GenProp0634 | Sigma-54 (RpoN) systems |
| GenProp0692 | selenouridine-containing tRNA |
| GenProp0704 | tRNA U34 carboxymethylaminomethyl modification |
| GenProp0740 | translation initiation, bacterial |
| GenProp0741 | translation elongation, bacterial |
| GenProp0746 | translation termination, bacterial |
| GenProp0812 | rho-dependent termination |