Genome Property Definition Page

Accession

GenProp0165

Name

minCDE system

Type

SYSTEM

Description

The MinCDE proteins are organized into extended membrane-associated coiled structures that wind around the cell between the two poles. These structures, and changes (pole-to-pole oscillations) in the distribution of the MinCDE proteins within them over time are required for the proper placement of the cell division septum at midcell [1,2]. This system is aparrently absent from Archaea, Actinobacteria, Bacteroides, Chlamydia, Staphylococci, Steptococci, Mollicutes and Spirochaetes.

JCVI Role

Cell division

Parent Property

GenProp0167: cellular growth, organization and division

Literature References

[ 1 ]Shih YL, Le T, Rothfield L. Division site selection in Escherichia coli involves dynamic redistribution of Min proteins within coiled structures that extend between the two cell poles. Proc Natl Acad Sci U S A. 2003 Jun 24; 100(13): 7865-70. Epub 2003 May 23. PMID 12766229
[ 2 ]Kruse K. A dynamic model for determining the middle of Escherichia coli. Biophys J. 2002 Feb; 82(2): 618-27. PMID 11806906

Gene Ontology Term

GO:0000918: barrier septum site selection (biological_process)

Components

Step Name	Step Num	Required	Evidence (Method)	Evidence Go Terms
MinC protein	minC	YES	TIGR01222 (HMM): septum site-determining protein MinC	GO:0000918: barrier septum site selection
MinD protein	minD	YES	TIGR01968 (HMM): septum site-determining protein MinD	GO:0000918: barrier septum site selection
MinE protein	minE	YES	TIGR01215 (HMM): cell division topological specificity factor MinE	GO:0000918: barrier septum site selection

Parent Properties

Accession	Name
GenProp0167	cellular growth, organization and division

Sibling Properties

Accession	Name
GenProp0049	spore formation
GenProp0166	mreBCD system
GenProp0173	cell shape
GenProp0201	SMC-ScpA-ScpB complex
GenProp0206	bacterial cell division septum system
GenProp0296	intracytoplasmic membranes
GenProp0460	gas vesicle
GenProp0678	c-type cytochrome biogenesis, system I
GenProp0680	c-type cytochrome biogenesis, system II