Genome Property Definition Page

AccessionGenProp0138
Nameiron-sulfur cluster assembly iscSUA-hscBA-fdx system
TypeSYSTEM
DescriptionAt least three different systems have been described for 2fe-2S cluster assembly. The NIF system provides an iron-sulfur cluster to nitrogenase in certain nitrogen-fixing species. SUF, described the most recently, can operate despite aerobic stress. This property describes the ISC system as found in E. coli and many other proteobacteria, containing at least the following elements: a characteristic cysteine desulfurase IscS, a characteristic ferredoxin, chaperones called heat shock cognate proteins A and B, and an assembly scaffold protein resembling the N-terminus of the scaffold protein of the NIF system.
JCVI RoleOther
Parent PropertyGenProp0140: iron-sulfur cluster assembly systems
Gene Ontology TermGO:0016226: iron-sulfur cluster assembly (biological_process)

Components
Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
FeS assembly iron donor CyaYCyaYYESTIGR03421 (HMM): iron donor protein CyaYGO:0016226: iron-sulfur cluster assembly
FeS assembly chaperone HscAHscAYESTIGR01991 (HMM): Fe-S protein assembly chaperone HscAGO:0016226: iron-sulfur cluster assembly
FeS assembly chaperone HscBHscBYESTIGR00714 (HMM): Fe-S protein assembly co-chaperone HscBGO:0016226: iron-sulfur cluster assembly
FeS assembly protein IscAIscAYESTIGR02011 (HMM): iron-sulfur cluster assembly protein IscAGO:0016226: iron-sulfur cluster assembly
iron-sulfur cluster assembly transcription factor IscRIscRYESTIGR02010 (HMM): iron-sulfur cluster assembly transcription factor IscR
cysteine desulfuraseIscSYESTIGR02006 (HMM): cysteine desulfurase IscSGO:0016226: iron-sulfur cluster assembly
iron-sulfur cluster assembly scaffoldIscUYESTIGR01999 (HMM): FeS cluster assembly scaffold IscUGO:0016226: iron-sulfur cluster assembly
FeS assembly protein IscX/YfhJIscXNOTIGR03412 (HMM): FeS assembly protein IscXGO:0016226: iron-sulfur cluster assembly
Isc-system ferredoxinfdxYESTIGR02007 (HMM): ferredoxin, 2Fe-2S type, ISC systemGO:0016226: iron-sulfur cluster assembly

Parent Properties
AccessionName
GenProp0140iron-sulfur cluster assembly systems


Sibling Properties
AccessionName
GenProp0137iron-sulfur cluster assembly SUF system
GenProp0739iron-sulfur cluster assembly CsdA-CsdE system
GenProp0742iron-sulfur cluster assembly NIF system