Genome Property Definition Page

NameNADH dehydrogenase I
DescriptionSeveral multichain membrane complexes couple electron transfer involving NADH to ion transport. This property represents an NADH dehydrogenase termed complex I, whose individual subunits are designated A through N. The electron acceptor is a quinone, ubiquinone, in most bacteria and in the related mitochondrial complex. The state for this property must be set to NO for related but distinct complexes, such as that from Methanosarcina in which F420H2 replaces NADH.
JCVI RoleElectron transport
Parent PropertyGenProp0131: electron transport
GenProp0180: small molecule transport
GenProp0612: aerobic electron transfer (transport) chain, ETC
Web ReferencesKEGG: Oxidative phosphorylation

Step NameStep NumRequiredEvidence (Method)Evidence Go Terms
NADH-ubiquinone/plastoquinone oxidoreductase, chain 3NuoAYESPF00507 (HMM): NADH-ubiquinone/plastoquinone oxidoreductase, chain 3
NADH dehydrogenase I, B subunitNuoBYESPF01058 (HMM): NADH ubiquinone oxidoreductase, 20 Kd subunit
TIGR01957 (HMM): NADH-quinone oxidoreductase, B subunit
NADH dehydrogenase I, C subunitNuoCYESPF00329 (HMM): respiratory-chain NADH dehydrogenase, 30 Kd subunit
TIGR01961 (HMM): NADH (or F420H2) dehydrogenase, subunit C
NADH dehydrogenase I, D subunitNuoDYESPF00346 (HMM): respiratory-chain NADH dehydrogenase, 49 kD subunit
TIGR01962 (HMM): NADH dehydrogenase (quinone), D subunit
NADH dehydrogenase I, E subunitNuoENOPF01257 (HMM): thioredoxin-like [2Fe-2S] ferredoxin
TIGR01958 (HMM): NADH-quinone oxidoreductase, E subunit
NADH dehydrogenase I, F subunitNuoFNOPF01512 (HMM): respiratory-chain NADH dehydrogenase 51 Kd subunit
TIGR01959 (HMM): NADH oxidoreductase (quinone), F subunit
NADH dehydrogenase I, G subunitNuoGNOTIGR01973 (HMM): NADH dehydrogenase (quinone), G subunit
NADH dehydrogenase I, H subunitNuoHYESPF00146 (HMM): NADH dehydrogenase
NADH dehydrogenase I, I subunitNuoIYESTIGR01971 (HMM): NADH-quinone oxidoreductase, chain I
NADH dehydrogenase I, J subunitNuoJYESPF00499 (HMM): NADH-ubiquinone/plastoquinone oxidoreductase chain 6
NADH dehydrogenase I, K subunitNuoKYESPF00420 (HMM): NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
NADH dehydrogenase I, L subunitNuoLYESTIGR01974 (HMM): proton-translocating NADH-quinone oxidoreductase, chain L
NADH dehydrogenase I, M subunitNuoMYESTIGR01972 (HMM): proton-translocating NADH-quinone oxidoreductase, chain M
NADH dehydrogenase I, N subunitNuoNYESTIGR01770 (HMM): proton-translocating NADH-quinone oxidoreductase, chain N

Parent Properties
GenProp0131electron transport
GenProp0180small molecule transport
GenProp0612aerobic electron transfer (transport) chain, ETC

Sibling Properties
GenProp0130Rnf-type electron transport complex
GenProp0177nickel-dependent hydrogenase
GenProp0119PTS transport system
GenProp0129Na+-translocating NADH-quinone reductase
GenProp0172Potassium-transporting ATPase KdpFABC
GenProp0176TRAP-T (tripartite ATP-independent periplasmic transporters) family transporters
GenProp0190phosphate ABC transporter (pstSCAB-phoU)
GenProp0191sulfate/thiosulfate ABC transporter
GenProp0192molybdate ABC transporter
GenProp0236phosphonates ABC transport
GenProp0252thiamine/TPP ABC transporter ThiBPQ
GenProp0279cobalt import systems
GenProp0494nickel import ABC transporter
GenProp0542Tol-Pal system
GenProp0543TonB-dependent transport
GenProp0651ectoine ABC transporter EhuABCD
GenProp0693fructose utilization as fructose-1,6-bisphosphate
GenProp0694glucose utilization as fructose-1,6-bisphosphate
GenProp07122-aminoethylphosphonate (AEP) ABC transporter, type I, PhnSTUV
GenProp07212-aminoethylphosphonate (AEP) ABC transporter, type II
GenProp0743urea ABC transporter UrtABCDE
GenProp0748choline ABC transporter, ChoXWV family
GenProp0749choline sulfate utilization
GenProp0828heme uptake system, NEAT-domain mediated
GenProp0853lantibiotic system, gallidermin/epidermin family
GenProp0873ion-motive antiporter cycles
GenProp0615cytochrome c based oxygen reduction and quinone re-oxidation
GenProp0616single complex oxygen reduction and quinone re-oxidation
GenProp0623NADH dehydrogenase, Sno(Mnh)ABCDEFG)