Genome Property Definition Page

Nametype IV pilus
DescriptionType IV pili, also called a type 4 fimbriae, are surface structures built from one major protein, pilin, oligomerized in a helical pattern to form a tube, and many minor structural proteins. Although usually found in gram-negative bacteria, there is one reported occurence found in the gram-positive speicies Streptococcus sanguis. Type IV pili can be used for flagellum-independent motility, called twitching motility (social gliding motility in Myxococcus xanthus), in which the pilus is extended, attached to a surface, and then retracted to drive the bacterium over a surface. Some genes for type IV pilus assembly are homologous to genes for type II protein secretion and competence for DNA uptake and transformation. Type IV pili may also be involved in conjugation, DNA transformation, pathogenesis, and phage infection [1].
Parent PropertyGenProp0069: cell surface component
GenProp0073: cell motility
GenProp0074: virulence
GenProp0076: DNA handling
Literature References
[ 1 ]Mattick JS.  Type IV pili and twitching motility.  Annu Rev Microbiol. 2002;56:289-314. Epub 2002 Jan 30.  PMID 12142488
[ 2 ]Carbonnelle E, Helaine S, Prouvensier L, Nassif X, Pelicic V  Type IV pilus biogenesis in Neisseria meningitidis: PilW is involved in a step occurring after pilus assembly, essential for fibre stability and function.  Mol Microbiol 2005 Jan;55(1):54-64.  PMID 15612916
Gene Ontology TermGO:0009289: pilus (cellular_component)

Parent Properties
GenProp0069cell surface component
GenProp0073cell motility
GenProp0076DNA handling

Sibling Properties
GenProp0012outer membrane
GenProp0158peptidoglycan(murein) biosynthesis
GenProp0297lipopolysaccharide biosynthesis
GenProp0326protein sorting system, PEP-CTERM/exosortase (generic)
GenProp0626protein sorting system, sortase type, LPXTG/SrtA class
GenProp0664protein sorting system, sortase type, SrtB class
GenProp0725outer membrane protein assembly complex
GenProp0811S-layer homology domain-mediated cell wall binding
GenProp0857anchored repeat-class ABC transporter, P. acnes type
GenProp0859protein sorting system, proteobacterial dedicated sortase type
GenProp0781gliding motility, Bacteroidetes type
GenProp0848actin-based motility of invasive bacteria
GenProp0032pathogen of plants
GenProp0049spore formation
GenProp0052type III secretion
GenProp0154intrinsic pathogen of animals
GenProp0648phage shock protein regulon
GenProp0707botulinum toxin system
GenProp0849quorum-sensing, Bacillus PlcR-PapR system
GenProp0018natural transformation
GenProp0115DNA repair
GenProp0198ruvABC Holliday junction complex
GenProp0311competence-related genes
GenProp0489F-type conjugation system
GenProp0490Ti-type conjugation system
GenProp0699DNA gyrase
GenProp0851integration host factor
GenProp0855integrating conjugative element, PFGI-1 class
GenProp0858conjugative transposon, Bacteroides type